The rules of transmission genetics are applied at the genomic scale in this novel method to estimate genotyping error rates at biallelic loci.
Description of contents:
R code that uses counts for each genotype-phase combination in a three-generation pedigree with five individuals to calculate genotyping error rates
Converts .vcf file with genotypes and .bed file with phases to a .txt file with genotype-phase combinations for input into R.
Simulates genotype-phase combinations from a three-generation pedigree assuming a neutral site frequency spectrum.