/AddQuality

Add Missing Quality Score to Bam FIle

Primary LanguagePython

AddQuality

Add Missing Quality Score to Bam FIle. Some mappers, e.g. LRA will generate bam file with some alignments's quality scores missed. Here I wrote a python scipt to restore those quality scores from the original fastq file. The quality scores are important information for SNPs and SV calling.

usage: python addQuality.py [-h] [-i IN_BAM] [-o OUT_SAM] [-f FASTQ]

Add missing query qualities to bam file

optional arguments: -h, --help show this help message and exit -i IN_BAM, --in_bam IN_BAM input bam file -o OUT_SAM, --out_sam OUT_SAM output sam file -f FASTQ, --fastq FASTQ fastq file used for mapping

Not recommended for large fastq files