RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting

This repository contains all the code used for data analysis in the paper above by Porfirio Quintero-Cadena, Tineke L. Lenstra and Paul W. Sternberg.

Requires python 3.6

analysis

Generate data that can be visualized: extract features from imaging, sequencing and simulation data.

figures

Generate all main and supplementary figures. Almost every figure* can be generated and saved in figures/output by running python figures/figureX.py from this directory, where X is the figure script suffix.

*Except for figures that require a file larger than github's 100MB size limit (Figures 6F, S2 and S8).

utils

Supporting functions for data analysis.

data

Output from analysis functions used to generate figures. Mostly csv files