1) MNI ADNI non-linear asymmetric Average Brain Stereotaxic Registration Model This is a version of the ADNI Average Brain - an average of ??? T1-weighted MRI scans, linearly and non-linearly (?? iterations) transformed to form an asymmetric model in Talairach space - that is specially adapted for use with the MNI Linear Registration Package (mni_autoreg). Included in this package are the following files: mni_adni_t1w_tal_nlin_asym.mnc: a version of the average MRI that covers the whole brain (unlike the original Talairach atlas), sampled with 1mm cubic voxels mni_adni_t1w_tal_nlin_asym_mask.mnc, mni_adni_t1w_tal_nlin_asym_mask.obj: a mask of the average brain in mni_adni_t1w_tal_nlin_asym.mnc.mnc, semi-automatically created by Vladimir Fonov. Note that this mask has had holes filled in, so it is a connected volume but includes non-brain tissue (eg. the CSF in the ventricles) mni_adni_t1w_tal_nlin_asym_headmask.mnc: another mask (full head mask), required for nonlinear mode mni_adni_t1w_tal_nlin_asym_vent.mnc, mni_adni_t1w_tal_nlin_asym_vent.obj: a mask of the ventricles mni_adni_t1w_tal_nlin_asym_ntags_1000_bg.tag: tag points for the background for mni_adni_t1w_tal_nlin_asym.mnc mni_adni_t1w_tal_nlin_asym_ntags_1000_nobg.tag tag points for the CSF, GM, and WM for mni_adni_t1w_tal_nlin_asym.mnc Cerebellum_Ventricles_SubCortical_Mask-ADNI.mnc: a template for the cerebellum, brain-stem, ventricles and sub-cortical gray to be used in the CIVET pipeline to_icbm152_2009a.xfm, to_icbm152_2009a_grid_0.mnc: a non-linear transform to map the ADNI model to the MNI-ICBM152-2009a model. 2) MNI ADNI non-linear symmetric Average Brain Stereotaxic Registration Model, hi-resolution This is a version of the ADNI Average Brain - an average of ??? T1-weighted MRI scans, linearly and non-linearly (?? iterations) transformed to form an asymmetric model in Talairach space - that is specially adapted for use with the MNI Linear Registration Package (mni_autoreg). The voxel resolution of this model is 0.5mm isotropic. Included in this package are the following files: mni_adni_hi_t1w_tal_nlin_sym.mnc: a version of the average MRI that covers the whole brain (unlike the original Talairach atlas), sampled with 1mm cubic voxels mni_adni_hi_t1w_tal_nlin_sym_mask.mnc, mni_adni_t1w_tal_nlin_asym_mask.obj: a mask of the average brain in mni_adni_t1w_tal_nlin_asym.mnc.mnc, semi-automatically created by Vladimir Fonov. Note that this mask has had holes filled in, so it is a connected volume but includes non-brain tissue (eg. the CSF in the ventricles) mni_adni_hi_t1w_tal_nlin_sym_headmask.mnc: another mask (full head mask), required for nonlinear mode mni_adni_hi_t1w_tal_nlin_sym_vent.mnc, mni_adni_hi_t1w_tal_nlin_sym_vent.obj: a mask of the ventricles mni_adni_hi_t1w_tal_nlin_sym_ntags_1000_bg.tag: tag points for the background for mni_adni_t1w_tal_nlin_asym.mnc mni_adni_hi_t1w_tal_nlin_sym_ntags_1000_nobg.tag: tag points for the CSF, GM, and WM for mni_adni_t1w_tal_nlin_asym.mnc gipt_adnihisym.mnc: a mask for sub-cortical gray that is used to define the sub-cortical tissue class in PVE Cerebellum_Ventricles_SubCortical_Mask-ADNIhi.mnc: a template for the cerebellum, brain-stem, ventricles, sub-cortical gray, hippocampus, amygdala, to be used in the CIVET pipeline hi_to_icbm152_2009b.xfm, hi_to_icbm152_2009b_grid_0.mnc: a non-linear transform to map the hi-res ADNI sym model to the MNI-ICBM152-2009b model (warning: it's not very accurate). 3) References: Fonov, V., Coupe, P., Eskildsen, S., Collins, L., and The Alzheimers’s Disease Neuroimaging Initiative (2011). Atrophy specific MRI brain template for Alzheimer’s disease and Mild Cognitive Impairment. Alzheimer’s Association International Conference, July 2011, France. 7 (4), pp. S58, 2011. https://hal.archives-ouvertes.fr/hal-00645521 https://drive.google.com/file/d/0B2WB9sZf0qcZTzUxZDU1QWRJRVE/view