/GSP_brain_decode_fingerprint

Primary LanguageMATLABApache License 2.0Apache-2.0

GSP_brain_decode_fingerprint

Implementation of brain decoding, fingerprinting, and behavior multivariate correlation analysis from structure-function coupling data (Structural Decoupling Index (SDI), coupled-Functional Connectivity (c-FC), decoupled-Functional Connectivity (d-FC)) and functional data (functional connectivity (FC) nodal strength, FC), as described in:

Brain structure-function coupling provides signatures for task decoding and individual fingerprinting
Alessandra Griffa, Enrico Amico, Raphaël Liégeois, Dimitri Van De Ville, Maria Giulia Preti
bioRxiv 2021.04.19.440314; doi: https://doi.org/10.1101/2021.04.19.440314

The SDI quantifies the degree of structure-function dependency for each brain region, and it has been defined in previous work:

Decoupling of brain function from structure reveals regional behavioral specialization in humans
Maria Giulia Preti, Dimitri Van De Ville
Nature Communications 10, article number 4747 (2019); https://doi.org/10.1038/s41467-019-12765-7

The c-FC and d-FC represent a decomposition of the classical functional connectivity information into a component coupled with structure, and a component more decoupled from structure. The two components are obtained by low-pass (high-pass) filtering time-resolved fMRI brain signals with respect to the structural connectome harmonics.

Code implementation

GSP_brain_decode_fingerprint is a collection of Matlab scripts.

Documentation

The documentation includes an Installation guide, Instructions to run the code, as well as Software requirements.

For questions, requesting assistance, suggesting enhancements or new ideas as well as for reporting bugs, please open an issue.