murine-vagina

vaginal inflation extension modeling

About the code:

This code was used in hyerelastic model fitting for published article: Akintunde AR, Robison KM, Capone DJ, Desrosiers L, Knoepp LR, Miller KS. Effects of Elastase Digestion on the Murine Vaginal Wall Biaxial Mechanical Response. ASME. J Biomech Eng. 2018;141(2):021011-021011-11 The code fits the Holzapfel-Gasser-Ogden (HGO) hyperelastic model (i.e. neo-Hookean + 2 fiber family of Fung exponential) to the pressure-diameter experimental data.

Running the code:

Easiest approach is to install anaconda software from Continuum Analytics. It has all the required python packages (numpy, scipy, matplotlib) and Spyder IDE.

Experimental Data:

Inflation (pressure-diameter) - extension (force-length) test data are in the .mat files contained in the Data folder. There are eight each for control and elastase samples according to the published journal article.

Sample Outputs:

Sample code outputs (plots and optimized parameter values) are in folder "control1".