/repertoire-embedding

Analyzing network structure of the known TCR-cognate epitope map

Primary LanguageJupyter NotebookApache License 2.0Apache-2.0

Repertoire sequencing data embedding tools

Simple scripts for embedding of immune repertoires represented as frequency-V-D-J-CDR3 clonotype tables:

  • Mapping of repertoires to a database of reference clonotypes
  • Prototype-based embedding optimized for repertoires (accounting for V/J, etc) to real space
  • 10X/decode data embedding
  • Hamming graphs for repertoires, community detection
  • Kmer-based representation of repertoires (smart K-mer family clustering)