I assume you have brew installed.
First install automake with brew:
brew install automake
Then just run:
./setup.sh
Also here is my own .screenrc. It defines a black hardstatus with window title list, selected window's background is blue,
user@hostname and time at the end of the line. Also white background captions for regions and gray background for focused.
One useful binding (if you don't use XON) Ctrl-a q kills all screens and quits.
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Sources:
setup.shis mostly based on this article: http://andrewho.co.uk/weblog/patching-gnu-screen-on-mac-os-x-for-vertical-splitvproc_priv.his from: https://github.com/pgib/screen