/SIMCCDA

Prediction of circRNA-disease associations based on inductive matrix completion.

Primary LanguageMATLAB

SIMCCDA

Title

Prediction of circRNA-disease associations based on inductive matrix completion.

Developers

Menglu Li (mengluli@foxmail.com) and Mengya Liu (woshiliangming@outlook.com ) from Institutes of Physical Science and Information Technology and School of Computer Science and Technology, Anhui University.

Related Files

Dataset:

========================================================================================
| FILE NAME            | DESCRIPTION                                                   |
========================================================================================
|chr_diseasematrix.csv | known circRNA-disease associations information, 1 indicates that circRNA and disease are associated, 0 indicates that their associations is currently in an unknown state.|
|dissimilarity.csv     | disease semantic similarity (DOSim (DOSE R package)).         |
|seqsimilarity.csv     | circRNA sequence similarity (Levenshtein distance).           |

Code:

========================================================================================
| FILE NAME       | DESCRIPTION                                                        |
========================================================================================
| main_LOOCV.m    | leave-one-out cross validation.                                    |
| SIMCCDA_demo.m  | function predicting potential circRNA-disease associations.        |
| gkl.m           | function computing Gaussian interaction profile kernel.            |
| PCA.m           | function extracting primary feature vectors via PCA.               |
| SIMC            | inductive matrix completion.                                       |
| roc.m           | function computing area under ROC curve.                           |

Contact

Please feel free to contact us if you need any help: jfxia@ahu.edu.cn.