TET2 Cannonical transcript not selected
Closed this issue · 3 comments
cpsosa0006 commented
The score is computed selecting Use Illumina's pre-computed scores: yes, result is:
Screenshot (optionally, paste or drag-drop an image here):
However, when selecting
The score is computed selecting Use Illumina's pre-computed scores: no, result is:
and the highest score is the canonical transcript with the highest score but it is not consistent when using yes. Why is the difference?
Thanks,
cpsosa0006 commented
Is this team still supporting spliceAI?
bw2 commented
Hi @cpsosa0006 , the Illumina pre-computed scores are based on gencode v26, while the other scores are based on gencode v42 - so that's the likely reason.
bw2 commented
I'm not part of the SpliceAI team. I just made this web server to look up or compute SpliceAI scores developed @ Illumina.