Handle VSQR variants differently
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rileyhgrant commented
Per Slack discussion.
Currently, the AS_VQSR
flag is treated the same as other variants when pulling variants for a gene, if the variant would be pulled per other criteria, it gets pulled and gets a filtered
flag applied to it, as in
- this list: https://genie.broadinstitute.org/dashboard/ENSG00000140598
- with this variant: https://gnomad.broadinstitute.org/variant/15-82220125-TG-T?dataset=gnomad_r4
To double check on what should be taken into account, it seems as though including them flagging them as filtered to let users decide what to do is reasonable, but perhaps there could be an option to not include filtered variants from gnomAD when pulling the initial list.