bwa-mem2/mm2-fast

Use learned-indexes based seeding with precomputed index?

schorlton opened this issue · 0 comments

Hi,

Thanks for your awesome work. Like original minimap2, is it possible to use a precomputed index (instead of FASTA file) with mm2-fast to save time?

Eg. in original minimap2, I may:

minimap2 -d index.mmi -ax map-ont reference.fasta
minimap2 -a index.mmi reads.fastq > output.sam

In current example, it looks like only a FASTA file is mentioned/supported as the index base. Alternatively, does mm2-fast even read the FASTA or does it only use its name to find the outputs from build_rmi.sh? Thanks!