qtl2mediat

qtl2mediate is R package for eQTl/pQTL mediation analysis.

Installation

You can install intermediate directly from Github using devtools package:

    # install.packages("devtools")
    devtools::install_github("byandell/intermediate")
    devtools::install_github("byandell/qtl2mediate")

Example

example(mediation_qtl2)

References

Joel M. Chick, Steven C. Munger, Petr Simecek, Edward L. Huttlin, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Karen L. Svenson, Gary A. Churchill & Steven P. Gygi: "Defining the consequences of genetic variation on a proteome-wide scale", Nature (2016) doi:10.1038/nature18270