This repository contains the codes used for analyses of FGFR3 E18-truncating rearrangements. Cohorts used in this study: Hartwig Medical Foundation (WGS and RNA-seq), Foundation Medicine (panel-seq)
HMF data
- genomic rearrangements of FGFR3 in HMF cohorts: HMF_data_purple_FGFR3.Rmd, HMF_data_purple_FGFR3.R
- matched RNA-seq profiles: HMF_FGFR3_RNAseq.R
FMI data
- genomic rearrangements of FGFR3 in FMI cohorts: FM_oncoplot.Rmd, FM_trunc.mut.Rmd
- FGFR2/FGFR3 rearrangement partner analysis: FM_FGFR3_partner_analysis.Rmd, FGF2_SID.Rmd
- co-alterating mutations with FGFR3 E18-truncations: FM_FGFR3_coalterations.Rmd