SigProfiler Module
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nicola-calonaci commented
The mutational signature deconvolution sub-workflow should have a SigProfileR process.
Please develop a python script that implements a best-practice routine of signature deconvolution.
The input Channel should take a text file produced from the CNAqc subwork-flow strarting from a multisample CNAqc object.
From this input a tri-nucleotide count matrix should be computed (python implementation of SparseSignatures::import.trinucleotides.counts() R function) and passed to the SigProfileR analysis routine.
nicola-calonaci commented
- Default parametrisation
- Updated singularity image
- Correct parsing of input K range
- Test run