STAMP is a suite of programs for the comparison and alignment of protein three dimensional structures. The suite will multiply align structures and produce a corresponding sequence alignment with confidence values associated with each aligned position. The software will also search a database of protein structures to identify structurally similar proteins. The suite includes a number of utility programs for the manipulation of protein structures. HOME http://code.google.com/p/bio-stamp/ DOWNLOAD https://code.google.com/p/bio-stamp/downloads/list INSTALL Do ./configure && make install You may need to be root to installed to the default location: ./configure && sudo make install Otherwise, specify an alternate directory installation prefix: ./configure --prefix=/usr/local && make install Or, if checked out from the source repository, then first do: autoreconf --install ./configure && make install If installing on Ubuntu, and the math library (libm) isn't found, do: LDADD=-lm make Once installed, you will want to edit the file: $prefix/share/stamp/pdb.directories to set the path and file pattern for your PDB files The file format is explained here: http://www.compbio.dundee.ac.uk/manuals/stamp.4.4/node57.html PROTEIN DATA BANK (PDB) AND DERIVED DATA To make use of STAMP, you will need to sync a local copy of the PDB: stamp-update-pdb [ /usr/local/data/pdb ] # Optionally, extract Domain definitions, Fasta sequences, and build a blast database: stamp-update-doms [ /usr/local/data/pdb ] [ /usr/local/data/pdbdom ] stamp-update-pdbseq [ /usr/local/data/pdbdom ] [ /usr/local/data/pdbseq ] stamp-update-blastdb [ /usr/local/data/pdbseq ] [ /usr/local/data/blastdb/pdbseq ] # Optionally, sync the biological unit assemblies: stamp-update-biounit [ /usr/local/data/biounit ] # Split biological assemblies into one file per model: stamp-update-biounit-models [ /usr/local/data/biounit ] You may also want to download DSSP definitions for PDB entries, e.g. : stamp-update-dssp [ /usr/local/data/dssp ] It is recommended to do all of the above in a crontab to remain up-to-date Note that the script aconvert has been removed. The script bp_sreformat from BioPerl does the same alignment format conversions. CITE Copyright (1997, 1998, 1999, 2010) Robert B. Russell & Geoffrey J. Barton. All use of the WORK must cite: R.B. Russell and G.J. Barton, "Multiple Protein Sequence Alignment From Tertiary Structure Comparison: Assignment of Global and Residue Confidence Levels", PROTEINS: Structure, Function, and Genetics, 14:309--323 (1992). LICENSE See COPYING MANUAL http://www.compbio.dundee.ac.uk/manuals/stamp.4.4/stamp.html BUGS https://code.google.com/p/bio-stamp/issues/list SOURCE https://code.google.com/p/bio-stamp/source/list CONTACT mailto:stamp@russelllab.org http://russelllab.org