chenxofhit/DoRC

Rare cells discovery, Single cell RNA-seq data, Isolation Forest

DoRC

DoRC is the abbreviation of Discovery of Rare Cells (DoRC), in the cost of minutes, from ultra-large scRNA-seq data.

Requirements of Python (version 3.7.1) packages

• MulticoreTSNE (https://github.com/DmitryUlyanov/Multicore-TSNE)
• FiRE (https://github.com/princethewinner/FiRE (branch: master))
• Pyod (https://pyod.readthedocs.io/en/latest/)
• sklearn, numpy, pandas, pickle...

thanks for all the authors' work!

Run

• run_dorc_68k_all.py: script for running DoRC in the pbmcs_68k dataset, which consists of 68579 PBMCs (www.10xgenomics.com)
• run_fire_68k_all.py: the same above but with FiRE instead.

Issues

Any question, please do not hesitate to contact me with chenxofhit@gmail.com, or submit issues here.