PopED computes optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix (FIM).
You need to have R installed. Download the latest version of R from www.r-project.org. You can install the released version of PopED from CRAN with:
install.packages("PopED")And the development version from GitHub with:
# install.packages("devtools")
devtools::install_github("andrewhooker/PopED")To get started you need to define
- A model.
- An initial design (and design space if you want to optimize).
- The tasks to perform.
Learn more in this introduction to PopED
You are welcome to:
- submit suggestions and bug-reports at: https://github.com/andrewhooker/PopED/issues
- send a pull request on: https://github.com/andrewhooker/PopED
- compose a friendly e-mail to: andrew.hooker@farmaci.uu.se