dejunlin/hicrep

AssertionError: Input cool files have different number of bins

Closed this issue · 2 comments

Hi,

Thanks for this wonderful tool.

I want to compare my .hic data with other downloaded .hic.
I used hic2cool to obtain .cool input but seems that there are difference in nbins.
HiC1.cool has "nbins": 3113 (1MB resolution)
HiC2.cool has "nbins": 3114 (1MB resolution)

Is there any way to fix this?
Any help is appreciated.

Best,

Hi, by definition, hicrep can only work on two contact matrices with the same underlying chromosome segmented into same number of bins. It's likely that you have some upstream data processing error, e.g., different assembly or bin definition. I don't think this is a hicrep issue

Closing as this is not a hicrep issue. Feel free to open new issues if find other problems of using the code