dpeerlab/SEACells

Custom Neighborhood Graph for Metacells

shahrozeabbas opened this issue · 0 comments

Hello,

I was wondering if it's possible to use a custom neighborhood graph for metacell construction. Looking through the source code and the tutorials, it seems that the methods depend on providing an anndata object with a low-dimension representation as input.

For example, if I wanted to build metacells using the wnn graph, would that be possible? Are there methods that I could use to create metacells by just providing the distances array from running scanpy.pp.neighbors or muon.pp.neighbors?

This would also be helpful for trying different values of k or different metrics for neighborhood graph construction.

Thanks for your input!