Results differ between web-interface and interproscan.sh
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Hello,
I noticed that the results for some sequences when run in web-interface differ compared to local runs from a fasta file.
For example this sequence:
>sequence1
MGSAMSLSCSKRKATSQDVDSESCKRRKICSTNDAENCIFIPDESSWSLCANRVISVAAVALTNFRFQQDNQESNSSSLSLPSPATSVSRNWKHDVFPSFHGADVRRTFLSHIMESFRRKGIDTFIDNNIERSKSIGPELKKAIKGSKIAIVLLSRKYASSSWCLDELAEIMKCREVLGQIVMTIFYEVEPTDIKKQTGEFGKAFTKTCRGKTKEHIERWRNALEDVATIAGYHSHKWRNEADMIEKIATDVSNMLNSCTPSRDFDGLVGMRAHMNMMEHLLRLDLDEVRIIGIWGPPGIGKTTIARFLLNQVSDRFQLSAIMVNIKGCYPRPCFDEYSAQLQLQNQMLSQMINHKDIMISHLGVAQERLRDKKVFLVLDEVDQLGQLDALAKETRWFGPGSRIIITTEDLGVLKAHGINHVYKVGYPSNDEAFQIFCMNAFGQKQPHEGFDEIAREVMALAGELPLGLKVLGSALRGKSKPEWERTLPRLRTSLDGKIGSIIQFSYDALCDEDKYLFLYIACLFNGESTTKVKELLGKFLDVRQGLHVLAQKSLISFHEEISCKQIVQVLLLNKFSHVRHTKRNNSQIIRMHTLLEQFGRETSRKQFVHHGYRKHQLLVGERDICEVLDDDTTDNRRFIGINLDLYKNEEELNISEKALERIHDFQFVKINDVFTHQPERQKLEDLIYHSPRIRSLKWFPYRNICLPSTFNPEFLVELDMSCSKLRKLWEGTKQLRNLKWMDLSNSRYLKELPNLSTATNLEELKLRNCSSLVELPSSIEKLTSLQILDLRDCSSLVKLPPSINANNVQGLSLTNCSRVVKLPAIENVTNLHQLKLQNCSSLIELPLSIGTANNLWKLDIRGCSSLVKLPSSIGDMTNLKEFDLSNCSNLVELPSSIGNLQKLFMLRMRGCSKLETLPTNINLISLRILDLTDCSQLKSFPEISTHISELRLKGTAIKEVPLSITSWSRLAVYEMSYFESLKEFPHALDIITYLLLVSEDIQEVPPWVKRMSRLRVLTLNNCNNLVSLPQLPDSLDHIYADNCKSLERLDCCFNNPEIRLYFPKCFKLNQEARDLIMHTSTRKYAMLPSIQVPACFNHRATSGDSLKIKLKESSLPTTLRFKACIMLVKVNEEMRDDEMWPSVLIAIRVKQNDLKVLCTASIYPVLTEHIYTFELEVEEVTSTELVFEFTPFLKSNWKIGECGILQRETRSLRRSSSPDLSPESSRAFSLSHSPLLSLCLMDWLMTRFLLMGFRCVSSCDHCL
gets annotated by Interproscan on the web interface (default settings) with Pfams:
PF01582
PF07725
PF00931
PF20160
This seems good and is pretty much what I am expecting
However, when running the same sequence through interproscan from command line (with -f TSV -app Pfam) as part of a larger fasta file it is only annotated as:
PF00004
This is an issue for me because I would like to have complete annotations for the genes, and it is kind of unclear to me why this happens. How can I get interproscan.sh to give me the same output as the web interface?
Additional information:
I have installed interproscan@5.66-98.0 via spack
This issue was resolved by downloading the full interproscan data and adding it to the spack installation. Appearently the data that comes with the spack package is incomplete.