/oneSC

infer transcription factors circuits, simulate single cell expression trajectories

Primary LanguagePython

OneSC (One tool to Simulate Cells)

OneSC is a 2-in-1 computational tool that does two things:

  1. Infer a functional transcription factors circuit that describe cell state transitions in the single-cell expression data

  2. Simulate synthetic single-cell expression profiles that mimic cell state transitions using the core transcription factors circuit as regulatory backbone

OneSC documentation is available through the link below.

Web documentation