gear-genomics/tracy

basecall problem

yuanzhao0502 opened this issue · 2 comments

I have a ab1 file tracy basecall only generate 121 bases but it visualized normal after that. What's the reason tracy can not doing the basecalling after that? Thank you for help!

7E983462-3D65-4fdf-AB43-0169030AC508

zip format of ab1 file

Tracy requires the original basecall positions from the Applied Biosystem machine. I guess in your case the machine terminated the Autoanalysis prematurely and thus, I would suggest to re-run the sequencing analysis on the machine.

Tracy requires the original basecall positions from the Applied Biosystem machine. I guess in your case the machine terminated the Autoanalysis prematurely and thus, I would suggest to re-run the sequencing analysis on the machine.

Thanks a lot for your suggest!

Actually I have a try to use biopython to read this file. "record.letter_annotations" can identify 972 bases. What's the differences of basecalling method between tracy and biopython?