Removal of SBS84, SBS85 from supervised example?

[DoaneAS]

Hi,

Thanks for this work- for the most part it's working nicely, however I'm not sure why you remove the last 2 cosmic3 signatures in the supervised tutorial:

# Subset reference data to create W matrix
Wref_df = ref_df.set_index('Somatic Mutation Type').iloc[:,:-2]

Perhaps for cosmic data you meant:

ref_df.set_index('Somatic Mutation Type').iloc[:,2:]

[shankara-a]

Hi @DoaneAS - I believe when I wrote this I was dropping the max_id and max_norm column that is automatically added when signatureanalyzer is initially run. Good catch that this would drop columns on reference data that does not have those columns.

[DoaneAS]

Hi @shankara-a, thanks- figured it was something like that. Thanks for SignatureAnalyzer!