gjhunt/dtangle

Cell type deconvolution from high-throughput gene expression profiling experiments.

dtangle: a method for cell-type deconvolution

we recommend using our updated deconvolution approach hspe, available here

Software

dtangle is an R package for cell type deconvolution.

• The R package is available on CRAN, on github, or from my box: package (source).

Vignettes

• Bulk RNA-seq and microarrays: here (html rmd)
• Using single-cell RNA-seq as references: here (html rmd)
• PBMC microarray deconvolution: here (html rmd)

Papers

1. "dtangle: accurate and robust cell type deconvolution" Bioinformatics (2019)

• Our publication in Bioinformatics is accessible here.

• Our docker image for reproducing the analysis in paper can be found here.

• A package dtangle.data of benchmark deconvolution data sets can be found here (source).

• The scripts for the analysis in our bioinformatics paper can be found here or here