/sb2021

SB2021 V1 Revision

Introduction

SB2021 Docking Database is a molecular docking validation dataset released by Rizzo Lab1 . However, the attached mol2 ligang files may cause many errors, therefore we used Flare V72 to check and fix the ligand structures.

Mateials

  1. ligand.tar.gz: co-crystal ligand structure in SDF format
  2. prot.tar.gz: co-crystal protein structure in PDB format. Pyflare was used to prepare the protein and the co-crystal ligand was extracted:
  3.   pyflare proteinprep.py -x 121p_ref.sdf ../prot/121p.pdb  >> 121p_prot.pdb
      

    Download link: prot.tar.gz

  4. id.lst: list of all systems

History

  1. 2024-01-22. Remove PDB 1ITV from data set because the ligand is a sulfate anion.
  2. 2024-01-21. Release ligand data set in SDF format.

Reference

  1. SB2021 Docking Database. Rizzo Lab. (Jan 21, 2024 accessed). https://ringo.ams.stonybrook.edu/index.php/SB2021.v1
  2. Flare V7. https://www.cresset-group.com/software/flare