gwlilabmit/rendseq

Add functionality for relevant biological questions

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Right now we have the ability to pull out some features from Rendseq data, but what would be really useful would be to automate our ability to connect these features to biological questions of interest. These include but are not limited to:

  • What is the distribution of terminator strengths in this organism. (we may not actually be able to read this - given the possibility of different upstream and downstream stability.....)
  • Can we estimate the number of reads that might be terminated by an intrinsic terminator vs those terminated by rho or a rho-like factor? (or perhaps a mix of both) (note - estimate, since there is some degree of uncertainty associated with the ramps, and with the peaks for that matter)
  • Annotate transcription units ie:
    • Where they are
    • Are they polycistonic?
  • Automate the ability to filter certain features across multiple conditions - ie - can we find all the peaks which change between these conditions?

Might add more to this list later. :)