Repository for DS501 Final Group Project
Measures are continuous
- sBCog45S: Brief Risk resilience Index for Screening Emotional/Cognitive Resilience
- sBNeg45S: Brief Risk resilience Index for Screening Negativity Bias
- sBSoc45S: Brief Risk resilience Index for Screening Social Connectedness
- sERQreap: Emotion Regulation Cognitive Reappraisal
- sERQsupp: Emotion Regulation Expressive Suppression
- sAnx42: Depression Anxiety Stress Scale Anxiety subscale
- sDepr42: Depression Anxiety Stress Scale Depression subscale
- sStres42: Depression Anxiety Stress Scale Stress subscale
- HDRS17: Hamilton Depression Rating Scale (17-item) Total
- sQIDS_tot: Quick Inventory Depressive Symptoms Total
- SOFAS_RAT: Social and Occupational Functinoal Assessment (SOFAS)
[Outcome Variable] 12 Cluster Derived Phenotypes (composition of questionnaire items from MDD surveys):
Measures are continuous in raw dataset scaled from 0-1 (with 1 being more MDD like). Measures are binary in cleaned dataset based on median (with 1 being high).
- Agitation_Slowing
- Disorganized_Pessimistic
- EmotionReappraisal
- Hopeless_Anhedonia_Avoition
- Insomnia_Energy
- Irritable_Agitated
- NegEmoImage
- Nervous_Anticipatory
- Sad_DepressedMood
- Social_Emotiol
- Social_Productive
- Somatic_PosSymp_Panic
Measures are binary 0 does not have, 1
- ANXIOUS_TYPE: Anxious depression subtype
- ATYPICAL_TYPE: Atypical depression subtype
- MELANCHOLIC_TYPE: Melancholic depression subtype
- Group: binary MDD or Control
- sex: categorical M and F
- Age: age in years numeric type with 2 decimal places
- Years_Education
- sBMI: BMI score
- MDD_DUR: Duration on depression in years
- TREATMENT: Drug treatment categories of 1, 2, 3 for MDD and treatment category of 4 for Control
- sELSTOT: Early Life Stress Total Score
- Response: binary yes or no responded to treatment
Averaging brain activity in EEG as a numeric variable. Two regions: P300 (part of brain for decision making and auditory oddball stimuli) and N1 (Visual evoked potential. attention). Measures for std and trg for min/max.
- std_N1_amp_min_pub_Fz
- std_N1_amp_min_pub_Cz
- trg_N1_amp_min_pub_Fz
- trg_N1_amp_min_pub_Cz
- std_P300_amp_max_Fz
- std_P300_amp_max_Cz
- std_P300_amp_max_Pz
- trg_P300_amp_max_Cz
- trg_P300_amp_max_Fz
- trg_P300_amp_max_Pz
118 SNPs in raw data. 101 SNPs in cleaned data after removing low cardinality SNPs. May need to remove even more SNPs in cleaned data. Number of alleles as a numeric variable from 0, 1, 2. Variable names start with rs. Last character is the DNA base pair for the SNP