horner/cellsim

Cell Division Simulator

cellsim

The use of javascript and d3-force to model cellular division.

Started based on https://bl.ocks.org/mbostock/31ce330646fa8bcb7289ff3b97aab3f5 Next goal is to add links between cells https://bl.ocks.org/mbostock/3180395

Playground

https://jsfiddle.net/5o82Ld0e/49/

Notes

• Time Lapse of C. elegans (12 hours of development) https://www.youtube.com/watch?v=M2ApXHhYbaw

• http://www.wormbook.org

• https://en.wikipedia.org/wiki/OpenWorm

• https://phys.org/news/2017-03-scientists-function-autophagy-germline-stem-cell.html

• https://www.sciencedirect.com/science/article/pii/S0012160618303452

• https://www.cherrybiotech.com/scientific-note/c-elegans-asymmetric-cell-division

  • Asymmetric Cell Division https://youtu.be/EaZOdrU1Du0&t=187
  • Stochastic, Niche, Asymmetric (Weismann,1880)
  • CDK5Rap2

• Controlling how many cells make a fly https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333400/

• Uncoupling of Longevity and Telomere Length in C. elegans - https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0010030

• The Systems Biology of Single-Cell Aging https://www.sciencedirect.com/science/article/pii/S2589004218301354

• d3-molecule https://arpitnarechania.github.io/d3-molecule/