ThermoProt is a python package to predict the thermostability of proteins. ThermoProt uses binary classifiers to predict the thermostability of proteins as
- psychrophilic vs. mesophilic (PM)
- mesophilic vs. thermophilic (MT)
- thermophilic vs. hyperthermophilic (TH)
- mesophilic vs. thermophlic/hyperthermophlic (MTH)
git clone https://github.com/jafetgado/ThermoProt.git
cd ThermoProt
conda env create -f ./env.yml -p ./env
conda activate ./env
python thermoprot/thermoprot.py --infile training_sequences/hyperthermophilic.fasta --outfile ./predictions.csv --modelname MTH
If you find ThermoProt useful, please cite the following:
Erickson E, Gado JE, et al, 2022. "Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity.