jhaaslab/elec_ffwd_inh_circuit

Electrical synapses and transient signals in feedforward canonical circuits

This is the code to run simulations in the paper:
Full title: Electrical synapses regulate both subthreshold and population activity of principal cells in response to transient inputs within canonical feedforward circuits
Link to paper on PLoS Comput Biol: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006440
Prepint of submission on bioRxiv: https://www.biorxiv.org/content/early/2018/08/17/394593
Authors: Tuan Pham (1) and Julie S. Haas (2)
Affiliation: Dept. of Biol. Sci., Lehigh University, Bethlehem, PA, USA
Contact: (1) phhanhtuanATgmailDOTcom, (2) julieDOThaasATlehighDOTedu, jhaaslabATgmailDOTcom

Requirements

• MATLAB R2018a
• Python 2.7
• Brian 2

File organization

• simulations contains simulation scripts in the following jupyter notebooks:
  • Subthreshold integration in canonical circuits: subthreshold_simumations.ipynb
  • Spiking responses in networks of canonical circuits: network_activity_simulations.ipynb
• prm_files contains neuron model parameters and network configuration parameters
• plotting_figures contains the MATLAB scripts for analysis and figure generation, using the functions in functions folder
• figures contains generated figures in the paper