Pinned Repositories
acidbase_fit
Estimation of rate constant parameters for the acid/base attack of aspirin. Post-graduate work for Dr. Desmond Williams at University of South Australia.
azithro_pk
Web application, raw code and digitised data for published manuscript: Hughes, J.H., Sweeney, K., Ahadieh, S. and Ouellet, D. (2020), Predictions of Systemic, Intracellular, and Lung Concentrations of Azithromycin with Different Dosing Regimens used in COVID‐19 Clinical Trials. CPT Pharmacometrics Syst. Pharmacol. Application can be found at:
calc_caff
Calcium Caffeine Model Simulations. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
comp_app
Web applications for use with compositional data. Post-graduate work for Dr. Dot Dimuid and Prof. Timothy Olds at University of South Australia.
empir_bayes
Empirical MAP Bayes examples and applications. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
NCAvNLME
Raw R code used in manuscript: Hughes JH, Upton RN, Foster DJR. Comparison of non-compartmental and mixed effect modelling methods for establishing bioequivalence for the case of two compartment kinetics and censored concentrations. J Pharmacokinet Pharmacodyn. 2017:1-12.
nivo_sim
Raw R code used in draft manuscript: Hughes JH, Roussin-Bouchard U, Wang Y, Boddy AV, Reuter SE. Reduction of Nivolumab Dosing using Adaptive-Dosage Strategies
otter_code
R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis. - Web App can be found at:
pfe_shiny_intro
Course materials for "Introduction to Shiny" internal course given in November 2020
shinyapps
Public apps and examples
jhhughes256's Repositories
jhhughes256/pfe_shiny_intro
Course materials for "Introduction to Shiny" internal course given in November 2020
jhhughes256/azithro_pk
Web application, raw code and digitised data for published manuscript: Hughes, J.H., Sweeney, K., Ahadieh, S. and Ouellet, D. (2020), Predictions of Systemic, Intracellular, and Lung Concentrations of Azithromycin with Different Dosing Regimens used in COVID‐19 Clinical Trials. CPT Pharmacometrics Syst. Pharmacol. Application can be found at:
jhhughes256/nivo_sim
Raw R code used in draft manuscript: Hughes JH, Roussin-Bouchard U, Wang Y, Boddy AV, Reuter SE. Reduction of Nivolumab Dosing using Adaptive-Dosage Strategies
jhhughes256/otter_code
R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis. - Web App can be found at:
jhhughes256/acidbase_fit
Estimation of rate constant parameters for the acid/base attack of aspirin. Post-graduate work for Dr. Desmond Williams at University of South Australia.
jhhughes256/calc_caff
Calcium Caffeine Model Simulations. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
jhhughes256/comp_app
Web applications for use with compositional data. Post-graduate work for Dr. Dot Dimuid and Prof. Timothy Olds at University of South Australia.
jhhughes256/empir_bayes
Empirical MAP Bayes examples and applications. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
jhhughes256/NCAvNLME
Raw R code used in manuscript: Hughes JH, Upton RN, Foster DJR. Comparison of non-compartmental and mixed effect modelling methods for establishing bioequivalence for the case of two compartment kinetics and censored concentrations. J Pharmacokinet Pharmacodyn. 2017:1-12.
jhhughes256/shiny-paganz
R code of Shiny workshop presented at PAGANZ 2017 in Adelaide.
jhhughes256/shinyapps
Public apps and examples
jhhughes256/carbo_app
Dosing application for manuscript: Harris, B.D.W., Phan, V., Perera, V. et al. Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes. Clin Pharmacokinet (2020). https://doi.org/10.1007/s40262-020-00870-6 - Web App can be found at:
jhhughes256/len_pbpk
Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Rozewski DM, Phelps MA, Foster DJR. Development of a physiologically-based pharmacokinetic model for intravenous lenalidomide in mice.
jhhughes256/LEN_PK
Raw R code used in manuscript: Hughes JH, Phelps MA, Upton RN, et al. Population pharmacokinetics of lenalidomide in patients with B-cell malignancies. Br J Clin Pharmacol. 2019;85(5):924-934.
jhhughes256/optinterval
Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis.
jhhughes256/vanc_tdm
Raw R code for simulations using South Australia Health Guidelines for vancomycin dosing. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.