Different Models showing similar results
Waleedkhan1122 opened this issue · 2 comments
Waleedkhan1122 commented
Hi GAPIT team,
I am using different models to obtain my GWAS results. I am facing an issue, the results of my most of the models are similar. Some models show completely same results such as FarmCPU and GLM. Please guide me what possibly I am doing wrong and how to resolve the issue. Thanks
jiabowang commented
Hi,
The FarmCPU is a multiple-step GWAS model, its first step is based on the GLM. If there are significant markers, they would be put into the next step as covariances.
So if there are no significant markers in the GLM, the final results of GLM and FarmCPU would be the same as each other.
Waleedkhan1122 commented
Thank you so much for your email. Thanks a lot.
Sincerely,
Waleed
…On Wed, Dec 27, 2023 at 12:06 PM Jiabo Wang ***@***.***> wrote:
Hi,
The FarmCPU is a multiple-step GWAS model, its first step is based on the
GLM. If there are significant markers, they would be put into the next step
as covariances.
So if there are no significant markers in the GLM, the final results of
GLM and FarmCPU would be the same as each other.
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