DestinyNet

Description

This repository contains the code for the paper "DestinyNet: A Deep Learning-Based Single-Cell Lineage Tracing Framework for Fate Clustering, Flow, and Prediction". The website is available in https://destinynet.readthedocs.io/en/latest/index.html

Introduction

We have developed a simple deep learning framework yet is able to encode single-cell RNA sequencing data, clonal information and descendant cell types of clones to decode the fate of any undetermined cell in three ways.

Model Architecture

How to Use?

Install the required environment
```
pip install -r requirements.txt
```
Install the latest version of DestinyNet
```
pip install DestinyNet
```
Modify the parameters in util.py, or use the default parameters

Example usage

import DestinyNet
args = DestinyNet.get_args()
DestinyNet.train(args)

Note