A small project for the Computational neuroscience course taught at University of Tartu.
Install python, jupyter notebook and the following modules
# Globally:
pip install jupyter
# In project folder:
Main functionality:
python -m pip install matplotlib
python -m pip install pandas
python -m pip install numpy
For ANOVA:
python -m pip install statsmodels
python -m pip install scipy
python -m pop install researchpy
! after installing statsmodels jupyter kernel wants a restart !
# Run notebook:
jupyter notebookAfter the environment is set up, create "data" folder in project folder, download demographic.csv and ERPdata.csv from Kaggle competition data, and put them into data folder.
Or change read_csv calls if you prefer some other folder :
demo = pd.read_csv("data/demographic.csv")
demo.columns = [col.replace(' ', '') for col in demo.columns]
erp_data = pd.read_csv("data/ERPdata.csv")- Did I Do That? Abnormal Predictive Processes in Schizophrenia When Button Pressing to Deliver a Tone
- Using concurrent EEG and fMRI to probe the state of the brain in schizophrenia
- Meditation (Vipassana) and the P3a event-related brain potential
- The N1-suppression effect for self-initiated sounds is independent of attention.
Our motor actions are preceded by a corollary discharge of the expected sensation in sensory cortex. This copy does not produce movement itself but it's directed to other regions of the brain to inform them of the following action. This mechanism is thought to be allowing animals to suppress responses which are self-generated, which helps to process sensational information more efficiantly.
We tried to replicate the results gotten by Judith M. Ford et al., 2013.
In was mentioned in that research paper that during talking patients with schizophrenia show less evidence of pretalking activity and less suppression of the speech sound. They tried to replicate the same effect with pressing a button followed by a tone. Their research included 26 schizophrenia patients and 22 healthy control subjects.
The data is gotten from Kaggle. We use ERP data from 9 electrodes from 32 control subjects and 49 schizophrenia patients.
As in the research that we follow, we also remove button-press activity from button-press-tone ERPs. We also measured N1 and P2 between 80 and 100 ms and 150 and 190 ms, respectively, as in the paper, after tone onset, relative to baseline (−100 to 0 ms) at frontal (Fz), frontal-central (FCz), and central (Cz).