/dropestr

Preprocessing of Droplet-based Single-Cell RNA-seq Data

Primary LanguageR

Build Status

dropestr

Perform UMI count corrections, and filtration of low-quality cells. Part of dropEst

Please see the vignettes:

Installation

devtools::install_github('kharchenkolab/dropestr')

Cell Filtration Procedure

Citation

If you find this software useful for your research, please cite the corresponding paper:

Petukhov, V., Guo, J., Baryawno, N., Severe, N., Scadden, D. T., Samsonova, M. G., & Kharchenko, P. V. (2018). dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments. Genome biology, 19(1), 78. doi:10.1186/s13059-018-1449-6