What number of mapped reads per cell is sufficient to detect a certain number of genes per cell?
I try to answer this question using GSE204750/SRX15446041 dataset. The authors report more than 500,000 mapped reads per cell.
The results are only applicable for K562 cell line and 10x Genomics 3' v3 droplet-based scRNA-seq.
At around 200,000 mapped reads per cell the number of detected genes per cell reaches a plato of 10-11,000 genes.
