This repository holds the data and source code for the following manuscript:
Mortberg MA & Gentile JE (equal contribution), Nadaf NM, Vanderburg C, Simmons S, Dubinsky D, Slamin A, Maldonado S, Petersen CL, Jones N, Kordasiewicz HB, Zhao HT, Vallabh SM, Minikel EV. A single-cell map of antisense oligonucleotide activity in the brain. Nucleic Acids Res. 2023 May 16:gkad371. doi: 10.1093/nar/gkad371. PMID: 37188501. PDF.
In this repository, you can:
- Download the analytical dataset
- Browse the figures and statistics that our scripts produce.
- Run our source code to reproduce the figures in the manuscript from the raw data. Just sync the repository and run
Rscript src/scaso_figures.R
. Note the package dependencies listed at the top of the script.
This work is licensed under a Creative Commons Attribution 4.0 International License.