Data packages for the research project "Exploratory analyses of GWAS data on PD" The data shared here form the bases of a metanalysis of genome-wide association studies (GWAS) with patients with panic disorder. The metanalysis produced a SNP list which was further analysed in R to produce a candidate gene list. This candidate gene list was further compared with data retrieved from GWASdb2. The resulting final list of candidate genes was analysed on the following databases:
- PathwayLinker, producing networks of interactors and a list of associated signaling pathways
- Brain RNA-Seq, producing median values of RNA-Seq data for expression in mouse cortex; these data were later processed via hierarchical cluster on Cluster 3.0
- Allen Human Brain Atlas, producing median values of microarray expression across 20 brain areas; these data were also processed via hierarchical cluster
- GeneNetwork / WebQTL, producing raw mRNA expression data, correlation matrices, and networks correlating behavioral data in BXD mice and mRNA levels of candidate genes in amygdala, hippocampus, prefrontal cortex, hypothalamus, and adrenal gland of mice.
