/FusionHunter

Identifying fusion transcripts using paired-end RNA-seq

Primary LanguageC

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# version1.4
# modification 2012/06/09
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    <one line to give the program's name and a brief idea of what it does.>
    Copyright (C) <2011>  <Yang Li (yangli9@illinois.edu)>

    This program is free software: you can redistribute it and/or modify
    it under the terms of the GNU General Public License as published by
    the Free Software Foundation, either version 3 of the License, or
    (at your option) any later version.

    This program is distributed in the hope that it will be useful,
    but WITHOUT ANY WARRANTY; without even the implied warranty of
    MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
    GNU General Public License for more details.

    You should have received a copy of the GNU General Public License
    along with this program.  If not, see <http://www.gnu.org/licenses/>.




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To install FusionHunter
type:
./install.sh

FusionHunter utilize perl package ForkManager. install.sh shall help you install ForkManager Package.
To install ForkManager package, you should have sudo permission




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FusionHunter use Bowtie as alignment tool. The bowtie and bowtie-build (all for 64-bit) are in path of FusionHunter/bin, 
if your mathine type is 32-bit, you can copy the executable file 'bowtie', 'bowtie-build' in FusionHunter/src/bowtie-0.12.7-linux-i386/ 
into FusionHunter/bin (replace the original ones for 64-bit)
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To run FusionHunter
copy the file FusionHunter.cfg to your working dir and edit variables in FusionHunter.cfg as indicated
then type following in your working dir:
DirtoFusionHunter/bin/FusionHunter.pl FusionHunter.cfg



For more information, please see http://bioen-compbio.bioen.illinois.edu/FusionHunter/

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Please cite: 

Li Y, Chien J, Smith DI, and Ma J. FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq. Bioinformatics, 27(12):1708-10, 2011.