Given the parents and the child. I want to measure the percentage of mutations in the SNPs(Single-nucleotide_polymorphism) genotypes. Then compare these mutated SNPs with SNPedia DB to identify risky mutations and % of mutation improvement. i.e:
Persona | SNP | Genotype |
Father | Rs7903146 | CT |
Mother | Rs7903146 | CT< |
Child | Rs7903146 | TT< |
Rs7903146 = "TT"
Magnitude = 3.5
Frecuency=10.6%
Repute=Bad: 2x increased risk for Type-2 diabetes-
References=286
http://www.snpedia.com/index.php/Rs7903146
Stats: Chromosome:1 0.72982454 simil Execution Time:1114ms - Reading and comparing with BufferedReader 1 Chromosome.
Input format (\t separated file):
# rsid chromosome position genotype
rs12564807 1 734462 AG
rs3131972 1 752721 GA
rs148828841 1 760998 TC
rs12124819 1 776546 AA