Bug: OverflowError when running hmmratac

[atj31]

I'm trying to run hmmratac to call peaks from my bampe files the code I used is
hmmratac -i Alignments/file.bam -f BAMPE --outdir Peaks/ -n name

It runs for a long time but I get an 'OverflowError: signed integer is greater than maximum' error

I tried to troubleshoot but unsure how to proceed - I can run the callpeak on the same bampe file without any issues.

Thank you in advance!

The whole running code pasted below:
[...]
INFO @ 19 Jun 2024 15:58:13: [428 MB] 37000000 fragments parsed
INFO @ 19 Jun 2024 15:58:16: [434 MB] 38000000 fragments parsed
INFO @ 19 Jun 2024 15:58:19: [441 MB] 38850552 fragments have been read.
INFO @ 19 Jun 2024 15:58:50: [441 MB] #2 Use EM algorithm to estimate means and stddevs of fragment lengths
INFO @ 19 Jun 2024 15:58:50: [441 MB] # for mono-, di-, and tri-nucleosomal signals...
INFO @ 19 Jun 2024 15:58:50: [441 MB] # A random seed 10151 has been used in the sampling function
INFO @ 19 Jun 2024 15:58:54: [491 MB] # Downsampled 1336693 fragments will be used for EM training...
INFO @ 19 Jun 2024 16:02:48: [491 MB] # Reached convergence after 11 iterations
INFO @ 19 Jun 2024 16:02:48: [491 MB] # The means and stddevs after EM:
INFO @ 19 Jun 2024 16:02:48: [491 MB] # short mono di tri
INFO @ 19 Jun 2024 16:02:48: [491 MB] # means: 50 173.9 381.2 600
INFO @ 19 Jun 2024 16:02:48: [491 MB] # stddevs: 20 53.6 51.4 20
INFO @ 19 Jun 2024 16:02:48: [491 MB] # Compute the weights for each fragment length for each of the four signal types
INFO @ 19 Jun 2024 16:02:55: [491 MB] # Generate short, mono-, di-, and tri-nucleosomal signals
Traceback (most recent call last):
File "/mnt/data/Utils/python_environ/macs3/bin/macs3", line 1028, in
main()
File "/mnt/data/Utils/python_environ/macs3/bin/macs3", line 101, in main
run( args )
File "/mnt/data/Utils/python_environ/macs3/lib/python3.9/site-packages/MACS3/Commands/hmmratac_cmd.py", line 155, in run
digested_atac_signals = generate_digested_signals( petrack, weight_mapping )
File "MACS3/Signal/HMMR_Signal_Processing.pyx", line 106, in MACS3.Signal.HMMR_Signal_Processing.generate_digested_signals
File "MACS3/Signal/HMMR_Signal_Processing.pyx", line 129, in MACS3.Signal.HMMR_Signal_Processing.generate_digested_signals
File "MACS3/Signal/BedGraph.pyx", line 219, in MACS3.Signal.BedGraph.bedGraphTrackI.add_chrom_data_hmmr_PV
File "MACS3/Signal/BedGraph.pyx", line 232, in MACS3.Signal.BedGraph.bedGraphTrackI.add_chrom_data_hmmr_PV
OverflowError: signed integer is greater than maximum