Protein-Protein Interaction (PPI) Network Annotation build

A library for annotating a protein-protein interaction network using differentially expressed gene information

INPUT FILES

There are 4 files which are necessary to run this program:

  1. A protein-protein interaction network in the format of:

    Entrez ID Entrez ID Confidence score

    Such as:

    216 216 0.76

    3679 1134 0.73

    55607 71 0.65

    5552 960 0.63

    2886 2064 0.9

    5058 2064 0.73

    1742 2064 0.87

    An example of such a network can be found [here](http://cbdm-01.zdv.uni-mainz.de/~mschaefer/hippie/download.php)

  2. An experiment file, in Excel format. Rows show individual entries, columns are the values of the following properties:

    • Log2 fold change
    • Adjusted p value
    • Entrez id

    The file may contain other columns too, but the indices and names of the above columns must be entered as parameters