Circulating Tumor DNA-Based Copy-Number Profiles Enable Monitoring Treatment Effects During Therapy in High-Grade Serous Carcinoma
- This github contains pipeline scripts and results from CNAs calling pipeline from targeted sequencing (Oseq) data.
- Tissue Biopsy and Plasma samples collected from High-Grade Serous Carcinoma (HGSC) patients
- There are 152 plasma samples collected longitudinally along the treatment to evaluate the genomic changes based on Copy-Number profiles
- Pipeline was built based on PureCN: https://bioconductor.org/packages/3.16/bioc/html/PureCN.html
- Mai TN. Nguyen - University of Helsinki
- Email: mai.tn.nguyen@helsinki.fi