Duardo_et_al_2024

Code for "Human DNA topoisomerase I poisoning causes R-loop-mediated genome instability attenuated by transcription factor IIS." 

by Duardo et al. Science Advances (2024)

This repositories contains scripts used to perform reads processing, alignment on reference genome, filtering and peak calling of DRIP-seq and END-seq reads. Folders contain DRIP-seq and END-seq peaks used in the analysis. Raw sequencing data and genomic signal tracks are available on GEO undee accession code GSE239328 For any information/issue please mail to marco.russo9@unibo.it.