/gapseq

Primary LanguageRGNU General Public License v3.0GPL-3.0

gapseq

Informed curation and gapfilling of metabolic networks

Example workflow

  1. Needed input files
  • Genome (fna)
  • Draft model (xml)
  1. Seed database corrections
  • python3 src/seedcorrect.py dat/myb71.xml
  1. Obtaining candidate reactions
  • ./gapseq.sh -p core dat/myb71.fna
  • ./gapseq.sh -p degradation dat/myb71.fna
  • ./transporter.sh dat/myb71.fna
  1. Gapfilling
  • Rscript gf.suite.R -m ./dat/myb71_corrected.xml -c ./dat/myb71-core-Reactions.lst,dat/myb71-degradation-Reactions.lst,dat/myb71-Transporter.lst -n dat/media/TSBmed.csv