/hla-antibody-analyzer

Electron app for performing HLA antibody analysis of reactivity panels

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HLA Antibody Analyzer

App for importing Single Antigen reactivity panels and performing automatic HLA antibody analysis.

Description

This is an Electron app developed to perform state-of-art in silico antibody analysis of Single Antigen reactivity panels belonging to patients waiting for a solid organ transplant. These panels are obtained by histocompatibility laboratories and their analysis enables immunologists to better choose the most immunologically compatible donor-recipient pairs for transplantation.

TODO

  • Create automated tests (in progress).
  • Improve CSS with the BEM methodology.
  • Group HLA alleles by locus.
  • Group HLA alleles by their 2-digit resolution.
  • Create charts to display the panel data.
  • Perform cluster analysis on MFI values.
  • Display MFI cutoff suggestions based on this research paper.
  • Perform virtual crossmatching based on the donor's HLA typing.
  • Add a print option.

Support

You can contact me at mariomarroquim@gmail.com.