An R package which implements the method described in:
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing
You can also find our preprint under: Data-driven hypothesis weighting increases detection power in multiple testing
The package can be installed as follows with devtools from the Github repositories:
devtools::install_github("vladchimescu/lpsymphony", subdir="lpsymphony")
devtools::install_github("nignatiadis/IHW")In addition, the package is available in the current release of Bioconductor (IHW). Thus IHW can also be installed from there as follows:
source("https://bioconductor.org/biocLite.R")
biocLite("IHW")