mgijax/mammalian-phenotype-ontology

abnormal CSF glucose level terms

Opened this issue · 3 comments

anna-anagnostop commented

J:281292 31399478 reports decreased CSF glucose levels in Slc2a1Rgsc200 heterozygotes. For now, I am annotating this to abnormal glucose homeostasis MP:0002078.

See https://en.wikipedia.org/wiki/CSF_glucose for causes of Low CSF glucose levels

Need to create new terms for:

abnormal cerebrospinal fluid glucose level
DEF: any deviation from the normal concentration of glucose in the cerebrospinal fluid
SYN: abnormal CSF glucose level
SOURCE: HP:0031884

decreased cerebrospinal fluid glucose level
DEF: less than the normal concentration of glucose in the cerebrospinal fluid
SYN: reduced cerebrospinal fluid glucose level
SYN: decreased CSF glucose level
SYN: reduced CSF glucose level
SYN: hypoglycorrhachia
SOURCE: HP:0011972, PMID:31399478

increased cerebrospinal fluid glucose level
DEF: greater than the normal concentration of glucose in the cerebrospinal fluid
SYN: elevated cerebrospinal fluid glucose level
SYN: increased CSF glucose level
SYN: elevated CSF glucose level
SYN: hyperglycorrhachia
SOURCE: HP:0031885

Should these be child terms of abnormal cerebrospinal fluid physiology MP:0021024 ? see child terms MP:0021027 and MP:0021082
Currently, there is no term available for abnormal cerebrospinal fluid composition.

anna-anagnostop commented

Added new terms:
abnormal cerebrospinal fluid glucose level MP:0031647
decreased cerebrospinal fluid glucose level MP:0031648
increased cerebrospinal fluid glucose level MP:0031649

anna-anagnostop commented

Move abnormal feces composition under digestive system morphology

TO DO:
Create new term abnormal cerebrospinal fluid composition under abnormal nervous system morphology.

Should level term in a bodily fluid be under physiology or under morphology branch?

anna-anagnostop commented

Moved abnormal feces composition under digestive system morphology