Visualizing Variability in Coronary Artery Disease Polygenic Risk Scores

This repository contains the code for a Shiny application that visualizes the variability in coronary artery disease (CAD) polygenic risk scores (PRS) across different populations.

The app is available at: https://mglev1n.github.io/CAD-prs-variability/.

This visualization tool accompanies the manuscript:

Abramowitz, S. A., Boulier, K., Keat, K., Cardone, K. M., Shivakumar, M., DePaolo, J., Judy, R., Kim, D., Rader, D. J., Ritchie, M., Voight, B. F., Pasaniuc, B., Levin, M. G.*, & Damrauer, S. M.* (2024). Population Performance and Individual Agreement of Coronary Artery Disease Polygenic Risk Scores. https://doi.org/10.1101/2024.07.25.24310931

*These authors jointly supervised this work.